Stable pharmaceutical compositions containing pravastatin

A - Human Necessities – 61 – K

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Details

A61K 9/20 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/22 (2006.01)

Patent

CA 2450001

Stabilized pharmaceutical preparations containing a drug which is sensitive to a low pH environment, such as pravastatin are disclosed in which pravastatin degradations is prevented with a buffering agent. The basic excipient enhances storage stability.

L'invention concerne des préparations pharmaceutiques stabilisées renfermant un médicament qui est sensible à un environnement de pH faible, par exemple à base de pravastatine. En l'occurrence, on empêche la dégradation de la pravastatine en utilisant un tampon. L'excipient de base améliore la stabilité de stockage du produit.

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