Detection of teratogen exposure

Details Detection of teratogen exposure Detection of teratogen exposure

G - Physics

01

N

G01N 30/02 (2006.01) G01N 33/92 (2006.01) G01N 30/06 (2006.01) G01N 30/72 (2006.01)

Patent

CA 2286576

The present invention relates to methods for detecting teratogen exposure in neonates. In particular, the present invention is directed to the detection of prenatal (i.e., in utero) exposure to ethanol. In accordance with the present invention, fatty acid ethyl esters, produced as the by-products of non- oxidative ethanol metabolism are detected in samples such as meconium and cord blood.

Cette invention se rapporte à des procédés pour détecter l'exposition de nouveau-nés à des agents tératogènes. Cette invention vise plus particulièrement à détecter l'exposition à l'éthanol au stade prénatal (c'est à dire in utero). Selon cette invention, des éthylesters d'acides gras, obtenus comme sous-produits du métabolisme de l'éthanol non oxidant, sont détectés dans des échantillons tels que le méconium et le sang du cordon.

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