C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/18 (2006.01) A61K 31/195 (2006.01) A61K 31/223 (2006.01) A61K 31/33 (2006.01) A61K 31/341 (2006.01) A61K 31/357 (2006.01) A61K 31/36 (2006.01) A61K 31/40 (2006.01) C07C 229/60 (2006.01) C07C 247/16 (2006.01) C07C 255/58 (2006.01) C07C 259/14 (2006.01) C07C 259/16 (2006.01) C07C 259/18 (2006.01) C07D 207/32 (2006.01) C07D 209/08 (2006.01) C07D 215/38 (2006.01) C07D 277/62 (2006.01) C07D 307/12 (2006.01) C07D 317/24 (2006.01) C07D 317/58 (2006.01) C07D 319/06 (2006.01) C07D 319/18 (2006.01)
Patent
CA 2272433
Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
L'invention concerne des composés qui inhibent la libération du peptide de .beta.-amyloïde et/ou sa synthèse et qui sont donc utiles dans le traitement de la maladie d'Alzheimer. Elle porte aussi sur des compositions pharmaceutiques comprenant un composé qui inhibe la libération du peptide de .beta.-amyloïde et/ou sa synthèse, ainsi que sur des méthodes de traitement de la maladie d'Alzheimer de manière thérapeutique et prophylactique à l'aide desdites compositions pharmaceutiques.
Audia James E.
Folmer Beverly K.
John Varghese
Latimer Lee H.
Nissen Jeffrey S.
Elan Pharmaceuticals Inc.
Eli Lilly & Company
Gowling Lafleur Henderson Llp
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