Tricyclic condensed heterocyclic compounds, their production...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/00 (2006.01) A61K 31/395 (2006.01) C07D 209/86 (2006.01) C07D 209/90 (2006.01) C07D 211/26 (2006.01) C07D 223/18 (2006.01) C07D 223/22 (2006.01) C07D 225/08 (2006.01) C07D 267/18 (2006.01) C07D 307/91 (2006.01) C07D 401/06 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/06 (2006.01) C07D 411/06 (2006.01) C07D 413/06 (2006.01) C07D 417/00 (2006.01) C07D 471/06 (2006.01) C07D 487/02 (2006.01) C07D 487/06 (2006.01) C07D 491/113 (2006.01)

Patent

CA 2113603

A novel compound of the formula: (see formula I) wherein Ar represents an optionally substituted tricyclic condensed benzene ring group which includes at least one heterocyclic ring as a component ring; n represents an integer from 2 to 10; R1 represents H or an optionally substituted hydrocarbon group, which may be different from one another in the repetition of n; and Y represents an optionally substituted 4-piperidinyl, 1-piperazinyl or 4- benzyl-1-piperidinyl group, or a salt thereof, inhibiting excellent cholinesterase inhibitory activity and monoamine reuptake inhibitory activity, thus being useful as therapeutic and/or prophylactic medicaments of senile dementia.

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