Method of detecting and monitoring prostate and ovarian cancers

Details Method of detecting and monitoring prostate and ovarian cancers Method of detecting and monitoring prostate and ovarian cancers

G - Physics

01

N

G01N 33/574 (2006.01)

Patent

CA 2448355

A method for the diagnosis, prognosis, and monitoring of ovarian or prostate cancer in a subject by detecting hK11 in a sample from the subject, preferably a serum sample. hK11 may be measured using a reagent that detects or binds to hK11 preferably antibodies specifically reactive with hK11 or a part thereof. Imaging methods for tumors associated with hK11 are also described using an agent that binds to hK11 which has a label for imaging the tumor.

L'invention concerne une méthode de diagnostic, de pronostic et de surveillance du cancer de la prostate ou de l'ovaire chez un sujet, ladite méthode reposant sur la détection de hK11 dans un échantillon prélevé chez ledit sujet, de préférence un échantillon de sérum. On peut mesurer hK11 en utilisant un réactif qui décèle ou se lie à hK11, de préférence à des anticorps particulièrement réactifs à hK11 ou à une partie correspondante. Ladite invention a aussi trait à des méthodes d'imagerie de tumeurs liées à hK11, ces méthodes employant un agent qui se lie à hK11 qui possède une étiquette destinée à l'imagerie de la tumeur.

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