A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/00 (2006.01) A61K 31/137 (2006.01) A61K 31/197 (2006.01) A61K 31/198 (2006.01) A61K 31/4045 (2006.01) A61K 31/417 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01)
Patent
CA 2297025
This invention provides a polymeric construct for delivering a biologically active agent to a mammal comprising a first polymeric matrix, a biologically active agent contained within the polymeric matrix, and a second polymer chemically bound to the biologically active agent, said second polymer comprising an amino acid copolymer, said second polymer present in an amount effective to reduce leakage of the active agent from the polymeric construct prior to delivery to the desired situs.
Cette invention concerne une construction polymère permettant d'administrer un agent biologiquement actif à un mammifère, laquelle construction comprend une première matrice polymère, un agent biologiquement actif contenu dans la matrice polymère et un second polymère chimiquement lié à l'agent biologiquement actif, ledit second polymère comprenant un copolymère d'acides aminés, ledit second polymère étant présent selon une dose efficace, pour réduire la fuite de l'agent actif de la construction polymère avant l'administration à l'emplacement voulu.
Geho W. Blair
Lau John R.
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