Once-a-day oxycodone formulations

Details Once-a-day oxycodone formulations Once-a-day oxycodone formulations

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61K 9/22 (2006.01) A61K 9/52 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2601289

The invention is directed to sustained release formulations containing oxycodone or a pharmaceutically acceptable salt thereof which provide a mean C24/C max oxycodone ratio of 0.6 to 1.0 or 0.7 to 1 after oral administration at steady state to patients and methods thereof.

L'invention porte sur des préparations à libération prolongée contenant de l'oxycodone ou un sel pharmaceutiquement acceptable de celui-ci et sur les méthodes relatives à ces préparations. Dans ces préparations, le rapport moyen C24/C max de l'oxycodone est de 0,6 sur 1,0 ou 0,07 sur 1 à l'état d'équilibre, après une administration par voie orale à des patients.

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