Substituted sulfonimidamides, processes for their...

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C - Chemistry, Metallurgy

07

C

C07C 381/10 (2006.01) A61K 31/18 (2006.01) A61K 31/33 (2006.01) C07D 207/34 (2006.01) C07D 213/60 (2006.01) C07D 295/155 (2006.01) C07D 307/56 (2006.01) C07D 333/30 (2006.01)

Patent

CA 2189221

Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them Sulfonimidamides of the formula I (see formula I) in which at least one of the three substituents R(1), R(2) and R(3) is a benzoylguanidine, and in which the other substituents have the meanings indicated in the claims, are outstandingly suitable as medicaments having action on the cardiovascular system; that is as antiarrhythmic pharmaceuticals having a cardioprotective component as well as for treating ischemically induced damage; also in operative interventions, such as organ transplantation.

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