Method of diagnosing colon and gastric cancers

Details Method of diagnosing colon and gastric cancers Method of diagnosing colon and gastric cancers

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7105 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) C07K 16/30 (2006.01) C12N 15/11 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2496885

Objective methods for detecting and diagnosing Colorectal and gastric carcinomas are described herein. In one embodiment, the diagnostic method involves the determining a expression level of colon or gastric cancer - associated gene that discriminate between colon or gastric cancer and nomal cell. The present invention further provides methods of screening for therapeutic agents useful in the treatment of colonic cancer and method of vaccinating a subject against colon or gastric cancer.

L'invention concerne des procédés permettant de détecter et de diagnostiquer des carcinomes colorectaux et gastriques. Dans une forme de réalisation, le procédé de diagnostic comporte l'étape consistant à déterminer le niveau d'expression d'un gène associé au cancer du côlon ou de l'estomac, qui permet de distinguer une cellule normale d'une cellule cancéreuse. L'invention concerne de plus des procédés de criblage d'agents thérapeutiques utiles dans le traitement du cancer du côlon et un procédé de vaccination d'un sujet contre le cancer du côlon ou de l'estomac.

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