Anti-epcam immunoglobulins

Details Anti-epcam immunoglobulins Anti-epcam immunoglobulins

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2555694

The invention relates inter alia to a method of treating tumorous disease in a human patient by administering to the patient a human immunoglobulin specifically binding to the human EpCAM antigen, the immunoglobulin exhibiting a serum half-life of at least 15 days, the method comprising the step of administering the immunoglobulin no more frequently than once every week, preferably no more frequently than once every two weeks.

L'invention concerne notamment un procédé permettant de traiter une maladie tumorale chez un patient humain en administrant à ce dernier une immunoglobuline humaine se liant spécifiquement à l'antigène EpCAM humain, ladite immunoglobuline présentant une demi-vie sérique d'au moins 15 jours. Ledit procédé consiste à administrer l'immunoglobuline au maximum une fois par semaine, de préférence au maximum une fois toutes les deux semaines.

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