Inhibitors of fatty acid synthase (fas)

Details Inhibitors of fatty acid synthase (fas) Inhibitors of fatty acid synthase (fas)

C - Chemistry, Metallurgy

07

D

C07D 215/48 (2006.01) A61K 31/47 (2006.01) A61P 35/00 (2006.01) C07D 401/10 (2006.01) C07D 409/10 (2006.01)

Patent

CA 2636018

The instant invention provides for compounds which comprise substituted 3-aryl- 4-hydroxyquinolin-2(1H)-ones that inhibit FAS activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting FAS activity by administering the compound to a patient in need of treatment of cancer.

La présente invention concerne des composés qui comprennent des 3-aryl-4-hydroxyquinolin-2(1H)-ones substituées qui inhibent l'activité de la FAS. L'invention concerne également des compositions qui comprennent de tels composés d'inhibition et des procédés d'inhibition de l'activité de la FAS par l'administration du composé à un patient ayant besoin d'un traitement contre le cancer.

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