Pharmaceutical compositions for the administration of aptamers

A - Human Necessities – 61 – K

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A61K 31/7088 (2006.01)

Patent

CA 2626368

Pharmaceutical compositions comprising an aptamer and an amino acid ester or amide or an aptamer; a divalent metal cation; and a carboxylic acid, a phospholipid, a phosphatidyl choline, or a sphingomyelin. Methods of treating or preventing a condition in an animal comprising administering to the animal the pharmaceutical compositions.

L'invention concerne des compositions pharmaceutiques comprenant un aptamère et un ester ou un amide d'aminoacide ou un aptamère ; un cation métallique divalent ; et un acide carboxylique, un phospholipide, une phosphatidylcholine ou une sphingomyéline. L'invention concerne également des méthodes de traitement ou de prévention d'un état chez un animal, ces méthodes consistant à administrer à cet animal lesdites compositions pharmaceutiques.

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