C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/195 (2006.01) A61K 38/16 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) A61P 35/00 (2006.01) C07K 14/21 (2006.01) G01N 33/566 (2006.01) C07K 14/705 (2006.01) C12N 9/12 (2006.01)
Patent
CA 2608512
The present invention relates to compositions and methods of use of cupredoxins, and variants, derivatives and structural equivalents of cupredoxins that interfere with the ephrin signaling system in mammalian cells. Specifically, the invention relates to compositions and methods that use cupredoxins, such as azurin, rusticyanin and plastocyanin, and variants, derivatives and structural equivalents thereof, to treat cancer in mammals.
L'invention concerne des compositions et des méthodes d'utilisation de cuprédoxines, et de variants, de dérivés et d'équivalents structuraux de cuprédoxines qui interfèrent avec le système de signalisation de l'éphrine dans des cellules mammifères. De manière spécifique, l'invention concerne des compositions et des méthodes faisant intervenir des cuprédoxines, de type azurine, rusticyanine et plastocyanine, et des variants, dérivés et équivalents structuraux associés, pour le traitement du cancer chez des mammifères.
Chakrabarty Ananda
Chaudhari Anita
Das Gupta Tapas
Fialho Arsenio
Yamada Tohru
Smart & Biggar
The Board Of Trustees Of The University Of Illinois
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