Thienopyridines as pharmacologically active agents

Details Thienopyridines as pharmacologically active agents Thienopyridines as pharmacologically active agents

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4743 (2006.01) A61P 3/10 (2006.01) A61P 19/02 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2748982

The present invention provides compounds and pharmaceutically acceptable salts thereof methods for synthesizing thienopyridines and methods for inhibiting TNF- .alpha. activity for the treatment of cancer, asthma, arthritis, diabetes and inflammation. Provided- are compounds of formula (I).

L'invention concerne des composés de formule (I) et des sels pharmaceutiquement acceptables de ceux-ci, ainsi que des procédés pour synthétiser des thiénopyridines et des procédés pour inhiber l'activité du TNF-a pour le traitement du cancer, de l'asthme, de l'arthrite, du diabète et des inflammations.

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