Surface-modifying endgroups for biomedical polymers

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 18/83 (2006.01) A61L 27/18 (2006.01) A61L 29/06 (2006.01) A61L 31/06 (2006.01) A61L 33/06 (2006.01) C08G 18/32 (2006.01) C08G 18/48 (2006.01) C08G 18/61 (2006.01)

Patent

CA 2186858

The present invention relates to novel polymeric compositions of matter and their use. Said polymeric compositions of matter are surface active endgroup-containing polymers that comprise a linear base polymer having covalently bonded surface active endgroups of a nature and present in an amount such that said polymers have a surface or interfacial tension that differs by at least 1 dyne/cm from the surface or interfacial tension of an otherwise identical polymer that does not contain said covalently bonded surface active endgroups. The novel linear polymers according to the present invention are particularly suitable for use in the manufacture of medical devices, and especially of medical devices intended to be used in contact with bodily fluids such as blood. Examples of such medical devices include catheters and artificial hearts.

La présente invention concerne de nouvelles compositions polymères et leurs utilisations. Lesdites compositions polymères sont des polymères contenant des groupes terminaux tensioactifs et qui comprennent un polymère de base linéaire, lié par covalence à des groupes terminaux tensioactifs de nature et en quantité telles que la tension superficielle ou interfaciale desdits polymères diffère d'au moins 1 dyne/cm par rapport à la tension superficielle ou interfaciale d'un polymère par ailleurs identique mais ne contenant pas lesdits groupes terminaux tensioactifs liés par covalence. Les nouveaux polymères linéaires selon la présente invention conviennent particulièrement à la fabrication d'instruments médicaux, et notamment d'instruments médicaux à utiliser au contact de fluides biologiques tels que le sang, par exemple les cathéters et les coeurs artificiels.

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