Spray-dried antigenic products and method of preparation

A - Human Necessities – 61 – K

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Details

A61K 39/02 (2006.01) A23K 1/16 (2006.01) A23K 1/18 (2006.01) A61K 39/106 (2006.01)

Patent

CA 2097830

A method is described for preparing an antigenic product which incorporates exposing an aerosol of a microbial suspension to temperatures at which substantially only the heat stable components of the microbial suspension retain their immunogenic properties. More specifically, the aerosol is exposed to an elevated temperature which denatures all labile components and removes the liquid portion of the aerosol by evaporation.

On décrit un procédé de préparation d'un produit antigénique qui consiste à soumettre un aérosol de suspension microbienne à des températures telles que pratiquement seuls les composants thermostables de ladite suspension conservent leur propriété immunogènes. Plus spécifiquement, on soumet l'aérosol à une température élevée, qui dénature tous les composants instables et enlève par évaporation la partie liquide de l'aérosol.

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