Vectors for gene mutagenesis and gene discovery

Details Vectors for gene mutagenesis and gene discovery Vectors for gene mutagenesis and gene discovery

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/80 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12N 15/867 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2323834

Novel vectors are described that incorporate, inter alia, a novel 3' gene trap cassette which can be used to efficiently trap and identify previously unknown cellular genes. Vectors incorporating the described 3' gene trap cassette find particular application in gene discovery and in the production of mutated cells and animals.

L'invention concerne de nouveaux vecteurs qui incorporent, entre autres, une nouvelle cassette de piégeage de gène 3' pouvant être utilisée pour piéger et identifier efficacement des gènes cellulaires jusqu'ici inconnus. Les vecteurs incorporant la cassette de piégeage de gène 3' décrite trouvent des applications particulières dans la découverte de gènes et dans la production de cellules et d'animaux mutés.

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