Use of tfpi to treat severe bacterial infections

Details Use of tfpi to treat severe bacterial infections Use of tfpi to treat severe bacterial infections

A - Human Necessities

61

K

A61K 38/57 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2607293

Methods for prophylactically or therapeutically treating a patient at risk of developing or diagnosed as having a severe bacterial infection involving administration of tissue factor pathway inhibitor (TFPI) or a TFPI analog to patients suffering from or at risk of developing this condition. The methods involve the use of continuous intravenous infusion of TFPI or a TFPI analog at low doses to avoid adverse side effects.

L'invention concerne des méthodes de traitement prophylactique ou thérapeutique d'un patient susceptible de développer ou chez qui on a diagnostiqué une infection bactérienne aiguë impliquant l'administration d'un inhibiteur de la voie du facteur tissulaire (TFPI) ou d'un analogue de TFPI destiné à des patients souffrant de cette affection ou susceptibles de la développer. Ces procédés consistent à utiliser une infusion intraveineuse continue de TFPI ou d'un analogue de TFPI en faibles quantités de manière à éviter les effets secondaires.

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