A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/14 (2006.01) C12N 5/078 (2010.01) A61K 38/18 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2309115
Method for ex-vivo inhibition of the production of immunoglobulins in a sample of peripheral blood mononuclear cells (PBMC) by addition of an inhibitory composition (e.g. containing IL-2 or TGF-beta as inhibitor agent) to the cells. Method of treating autoimmune diseases, e.g. systemic lupus erythematosus (SLE), by reintroducing the treated cells to a patient.
L'invention concerne un procédé visant l'inhibition ex vivo de la production d'immunoglobulines dans un échantillon de cellules mononucléaires de sang périphérique par addition d'une composition inhibitrice (contenant par exemple de l'IL-2 ou du TGF-bêta comme agent inhibiteur) aux cellules. L'invention comprend également un procédé permettant de traiter des maladies autoimmunes, par exemple le lupus érythémateux disséminé, en réintroduisant chez le patient les cellules traitées.
Riches Mckenzie & Herbert Llp
University Of Southern California
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