Osteogenic peptides

Details Osteogenic peptides Osteogenic peptides

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61L 27/00 (2006.01) A61L 27/22 (2006.01) C07K 14/51 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2094027

Disclosed are 1) the cDNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogen- ic proteins, 2) osteogenic devices comprising these proteins in association with an appropriate carrier matrix, 3) methods of prod- ucing the polypeptide chains using recombinant DNA technology, and 4) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.

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