Nope polypeptides, encoding nucleic acids and methods of use

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2396355

The invention provides an isolated Nope polypeptide, or functional fragment thereof, containing the amino acid sequence of a Nope polypeptide (SEQ ID NO: 2), or a modification thereof. The invention also provides an isolated nucleic acid molecule encoding a Nope polypeptide amino acid sequence referenced as SEQ ID NO: 2, or a modification thereof. The invention additionally provides an isolated nucleic acid molecule containing the nucleotide sequence referenced as SEQ ID NO: 1, or a modification thereof. The invention further provides methods of detecting Nope polypeptides and Nope nucleic acid molecules.

La présente invention concerne un polypeptide Nope isolé, ou l'un de ses fragments fonctionnels, contenant la séquence d'acide aminé d'un polypeptide Nope (SEQ ID NO: 2), ou l'une de ses modifications. L'invention concerne également une molécule d'acide nucléique isolée codant une séquence d'acide aminé du polypeptide Nope (SEQ ID NO: 2), ou l'une de ses modifications. L'invention concerne aussi une molécule d'acide nucléique isolée contenant la séquence de nucléotides SEQ ID NO: 1, ou l'une de ses modifications. L'invention concerne enfin un procédé permettant de détecter des polypeptides Nope et des molécules d'acide nucléique Nope.

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