Process for the manufacture of hmg-coa reductase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 215/14 (2006.01) C07B 53/00 (2006.01) C07D 209/18 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2472776

The invention relates to a process for the manufacture of a compound of formula (I) or a salt, especially a pharmaceutically acceptable salt with a base, thereof or a lactone thereof wherein the element (II) represents -CH2- CH2- or -CH=CH- and R represents a cyclic residue.

La présente invention concerne un procédé permettant la préparation d'un composé de formule (I) ou d'un sel, notamment d'un sel pharmaceutiquement acceptable avec une base, de celui-ci, ou une lactone de celui-ci, l'élément (II) représentant -CH¿2?-CH¿2?- ou -CH=CH- et R représentant un résidu cyclique.

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