Flagellin gene, flac of campylobacter

Details Flagellin gene, flac of campylobacter Flagellin gene, flac of campylobacter

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 31/70 (2006.01) A61K 39/106 (2006.01) C07K 14/205 (2006.01) C07K 16/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2224127

Purified and isolated nucleic acid molecules are provided which encode a FlaC flagellin protein of a strain of Campylobacter, particularly C. jejuni, or a fragment or an analog of the FlaC flagellin protein. The nucleic acid molecules may be used to produce proteins free of contaminants derived from bacteria normally containing the FlaA or FlaB proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules, proteins encoded thereby and antibodies raised against the proteins, may be used in the diagnosis of infection.

Molécules d'acide nucléique purifiées et isolées codant pour une protéine flagelline FlaC d'une souche de Campylobacter, notamment C. jejuni, ou un fragment ou un analogue de la protéine flagelline FlaC. Les molécules d'acide nucléique peuvent servir à produire des protéines exemptes de contaminants dérivées de bactéries contenant normalement des protéines FlaA ou FlaB aux fins de diagnostics et de traitements médicaux. En outre, les molécules d'acide nucléique, les protéines qu'elles codent et les anticorps libérés contre les protéines peuvent servir à diagnostiquer une infection.

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