A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/57 (2006.01)
Patent
CA 2202989
This invention is directed to a method of attenuating or preventing the adverse side-effects of a perfluorochemical (PFC) emulsion on the hemostatic system and serum chemistry of an animal. The method includes intravenously administering a corticosteroid to an animal prior to intravenous administration of a PFC emulsion, in an amount sufficient to improve the adverse effects of the PFC upon the hemostatic system and serum triglyceride/enzyme levels of the animal. After administration of the corticosteroid, the PFC emulsion is administered intravenously. Preferably, the corticosteroid is dexamethasone, and the PFC is perfluorodichlorooctane.
Procédé permettant d'atténuer ou d'empêcher les effets secondaires néfastes d'une émulsion perfluorochimique (PFC) sur le système hémostatique et la chimie du sérum d'un animal. Ledit procédé consiste à administrer par voie intraveineuse un corticostéroïde à un animal avant l'administration intraveineuse d'une émulsion PFC, en une quantité suffisante pour améliorer les effets secondaires néfastes de la PFC sur le système hémostatique et les taux sériques de triglycérides/enzymes dudit animal. Après administration du corticostéroïde, l'émulsion PFC est administrée par voie intraveineuse. De préférence le corticostéroïde est de la dexaméthasone, et la PFC est du perfluorodichlorooctane.
Goodin Thomas H.
Kaufman Robert J.
Hemagen/pfc
Macrae & Co.
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