Methods for constructing antibiotic resistance free vaccines

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/68 (2006.01)

Patent

CA 2577306

The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.

La présente invention concerne des souches vaccinales de Listeria exprimant un antigène hétérologue et une enzyme métabolique ainsi que des procédés de production de ces souches.

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