Polypeptide markers for the diagnosis of alzheimer's disease

G - Physics – 01 – N

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G01N 33/68 (2006.01)

Patent

CA 2604033

The invention relates to a method for diagnosing Alzheimer's disease. In said method, the presence or absence of at least one polypeptide marker in a sample is determined, said polypeptide marker being selected from markers 1-50 (frequency markers), or the amplitude of at least one polypeptide marker is determined, selected from markers 51-279 (amplitude markers), which are characterised by the following values for molecular masses and migration time:

L'invention concerne un procédé de diagnostic d'Alzheimer, comprenant l'étape de détermination de la présence, ou de l'absence, d'au moins un marqueur de polypeptide dans un échantillon, ledit marqueur de polypeptide étant choisi parmi les marqueurs 1-50 (marqueur de fréquence), ou la détermination de l'amplitude d'au moins un marqueur de polypeptide, choisi parmi les marqueurs 51-279 (marqueur d'amplitude) qui sont caractérisés par les valeurs suivantes pour les masses moléculaires et les temps de migration.

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