C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) C07K 14/40 (2006.01) G01N 33/50 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2351017
The invention concerns the Candida albicans transcription factor hereafter referred to as CATFIIIA and its analogues as well as the polynucleotides (RNA, DNA) coding for said protein or for polypeptides analogues of said protein. The invention also concerns the method for preparing said polypeptides and polynucleotides, their use for preparing inhibitors of said transcription factor CATFIIIA capable of being used as antifungal agents and pharmaceutical compositions containing said inhibitors.
La présente invention concerne le facteur de transcription de Candida albicans nommé ci-après CATFIIIA et ses analogues ainsi que les polynucléotides (ARN, ADN) codant pour cette protéine ou pour les polypeptides analogues de cette protéine et également le procédé de préparation de ces polypeptides et polynucléotides, leur utilisation pour la préparation d'inhibiteurs de ce facteur de transcription CATFIIIA pouvant être utilisés comme agents antifongiques et les compositions pharmaceutiques contenant de tels inhibiteurs.
Bordon-Pallier Florence
Camier Sylvie
Sentenac Andre
Aventis Pharma S.a.
Robic
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