Use of plant extract for inhibition of haemophilus influenzae

A - Human Necessities – 61 – K

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Details

A61K 47/00 (2006.01) A61K 9/20 (2006.01) A61K 9/68 (2006.01) A61P 11/04 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2280940

The attachment of H. influenzae to human cells such as oropharyngeal cells, is inhibited by aqueous extracts of the plants known as Pogostemon cablin and Agastache rugosa. The composition obtained from the aqueous extraction of the plants Pogostemon cablin, Agastache rugosa or mixtures thereof is also effective in preventing or treating Otitis media and sore throat. The plant extract may be contained in a liquid enteral product such as an infant formula or may be incorporated into lozenges, candies, chewing gums and the like. The plant extract may also be administered as a throat spray or nasally using drops or a spray. A process for the production of a medicinal product is also disclosed.

La présente invention permet d'inhiber la fixation du H. influenzae sur les cellules humaines telles que les cellules oropharyngées au moyen d'extraits aqueux de plantes connues sous le nom de Pogostemon cablin et Agastache rugosa. La composition obtenue à partir de l'extrait aqueux des plantes Pogostemon cablin et Agastache rugosa, ou de mélanges de celles-ci, est également efficace dans la prévention ou le traitement de l'otite moyenne et de l'angine. L'extrait végétal peut être contenu dans un produit liquide entéral tel qu'une préparation pour nourrissons ou il peut être incorporé dans des pastilles, des bonbons, des pâtes masticatoires et produits analogues. L'extrait végétal peut également être administré sous forme de nébuliseur pour la gorge, de gouttes nasales ou de nébuliseur pour le nez. L'invention concerne également un procédé de production d'un produit médical.

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