Substituted-3-benzyl-benzofurans

Details Substituted-3-benzyl-benzofurans Substituted-3-benzyl-benzofurans

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/34 (2006.01) A61K 31/395 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07D 307/81 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2171399

This invention relates to the fields of pharmaceutical and organic chemistry and provides novel 3- benzyl-benzofurans which are .alpha.-substituted with ether, thioether, amino, hydrazino cyano or halo that are useful for the treatment of the various medical indications associated with post-menopausal syndrome, as well as estrogen dependent diseases including cancer of the breast, uterus and cervix. The present invention further relates to intermediate compounds and processes useful for preparing the pharmaceutically active compounds of the present invention, and pharmaceutical compositions.

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