A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/04 (2006.01) A61K 38/00 (2006.01) C07K 5/00 (2006.01) C07K 7/06 (2006.01)
Patent
CA 2690734
Described herein are fragments of fibronectin and vitronectin and variants thereof that have certain activities, including growth factor-binding activity. Also described are fragments of growth factors that bind to fibronectin and inhibit binding of full-length growth factors to fibronectin. Compositions containing such fragments are useful in cosmetic treatments (e.g., the treatment of wrinkles or UV photodamage of skin), and the treatment of wounds and cancer.
L'invention porte sur des fragments de fibronectine et de vitronectine et des variants de ces derniers qui possèdent certaines activités, y compris une activité de liaison au facteur de croissance. L'invention se rapporte également à des fragments de facteurs de croissance qui lient la fibronectine et inhibent la liaison des facteurs de croissance de pleine longueur à la fibronectine. L'invention concerne des compositions contenant lesdits fragments, qui sont utilisées dans des traitements cosmétiques (p.ex., le traitement des rides ou de l'altération cutanée due aux UV) et dans le traitement des plaies et du cancer.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Research Foundation Of State University Of New York
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