Method and apparatus for isolating 186rhenium

B - Operations – Transporting – 01 – D

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B01D 59/42 (2006.01) A61K 51/04 (2006.01)

Patent

CA 2682383

A method of isolating 186Re according to example embodiments may include vaporizing a source compound containing 185Re and 186Re. The vaporized source compound may be ionized to form negatively-charged molecules containing 185Re and 186Re. The negatively-charged molecules may be separated to isolate the negatively-charged molecules containing 186Re. The isolated negatively-charged molecules containing 186Re may be collected with a positively-charged collector. Accordingly, the isolated 186Re may be used to produce therapeutic and/or diagnostic radiopharmaceuticals having higher specific activity.

L'invention concerne un procédé destiné à isoler 186Re. Selon certains modes de réalisation, le procédé peut comprendre la vaporisation d'un composé source qui contient 185Re et 186Re. Le composé source vaporisé peut être ionisé pour former des molécules chargées négativement qui contiennent 185Re et 186Re. Les molécules chargées négativement peuvent être séparées pour isoler les molécules chargées négativement qui contiennent 186Re. Les molécules chargées négativement isolées qui contiennent 186Re peuvent être recueillies avec un collecteur chargé positivement. Le 186Re isolé peut être utilisé pour fabriquer des produits radiopharmaceutiques pour la thérapie et/ou le diagnostic qui présentent une activité spécifique supérieure.

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