Hydrophobic derivatives of natural biodegradable...

A - Human Necessities – 61 – L

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A61L 31/04 (2006.01) A61F 9/00 (2006.01) A61K 9/00 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2645324

Hydrophobic derivatives of natural biodegradable polymers and uses thereof are described. The derivatives are exemplified by low molecular weight hydrophobic derivatives of .alpha.(1.fwdarw.4)glucopyranose polymers and non-reducing polysaccharides. The hydrophobic polysaccharides can be formed matrices for various uses, including body members of implantable articles, coatings, and consumer items. The matrices have desirable properties, which are advantageous for use in vivo.

Cette invention concerne, d'une part, des dérivés hydrophobes de polymères biodégradables et, d'autre part, leurs utilisations. Ces dérivés sont illustrés par des dérivés hydrophobes à faible poids moléculaire de polymères .alpha.(1.fwdarw.4)glucopyranose et des polysaccharides non-réducteurs. Les polysaccharides hydrophobes peuvent être des matrices formées pour diverses utilisations, y compris pour des éléments constitutifs d'articles implantables, des revêtements et des articles de consommation. Ces matrices présentent des propriétés souhaitables et elles sont avantageusement utilisées in vivo.

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