Treatment of microbial infections and associated...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 1/00 (2006.01) A61P 31/00 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2475053

Microbial infections including anthrax infection, and gastrointestinal disorders, are treated or prevented by administration of an actin-sequestering peptide including amino acid sequence LKKTET, such as Thymosin .beta.4, an isoform of Thymosin .beta.4, oxidized Thymosin .beta.4, or T.beta.4 sulfoxide.

L'invention concerne le traitement ou la prévention d'infections microbiennes, y compris l'infection au charbon bactérien, et de maladies gastro-intestinales, par administration d'un peptide de séquestration d'actine renfermant la séquence d'acides aminés LKKTET, du type thymosine .beta.4, isoforme de thymosine .beta.4, thymosine .beta.4 oxydée, ou sulfoxyde T.beta.4.

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