Transport protein which effects the transport of cationic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2153756

Transport protein which effects the transport of cationic xenobiotics and/or pharmaceuticals, DNA sequences encoding it and their use A transport protein has been cloned which is present in liver epithelial cells and kidney epithelial cells and in intestinal cells and is responsible for transporting cationic pharmaceuticals and/or xenobiotics. This transport protein has been described more specifically by its DNA and amino acid sequences, and various uses are disclosed which are, in particular, of great importance for developing novel medicaments.

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