Alpha-cyano-beta-oxopropionamides

Details Alpha-cyano-beta-oxopropionamides Alpha-cyano-beta-oxopropionamides

C - Chemistry, Metallurgy

07

D

167/207, 167/268

C07D 213/57 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 261/08 (2006.01) C07D 277/30 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2004754

NOVEL ALPHA-CYANO-BETA-OXOPROPIONAMIDES ABSTRACT OF THE INVENTION .alpha.-(Substituted carbamoyl)-.beta.-aryl- and heteroaryl-.beta.-oxo-propionitriles of formula Image (I), enol ethers thereof and salts thereof, as well as pharmaceutical preparations containing same and methods of preparing and using these compounds are disclosed. Said compounds represent novel antiinflammatory and antirheumatic agents. Their property to interfere with both the cyclooxygenase and lipoxygenase pathway of the arachidonic fatty acid bioconversion to inflammatory mediators make them valuable therapeutics. These properties render the mentioned substituted carbamoyl-.beta.-oxopropionitriles useful for the treatment of arthritic and rheumatic diseases and other inflammatory conditions in mammals.

Affiliated with

Also associated with

Rating

Alpha-cyano-beta-oxopropionamides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alpha-cyano-beta-oxopropionamides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alpha-cyano-beta-oxopropionamides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1667095