Melanin-concentrating hormone analogs

Details Melanin-concentrating hormone analogs Melanin-concentrating hormone analogs

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/00 (2006.01) C07K 7/52 (2006.01) C07K 14/575 (2006.01)

Patent

CA 2399509

The present invention features truncated MCH analogs active at the MCH receptor. The truncated MCH analogs are optionally modified peptide derivatives of mammalian MCH. The analogs can bind to the MCH receptor and, preferably, bring about signal transduction. MCH analogs have a variety of different uses including being used as a research tool and being used therapeutically.

La présente invention concerne des analogues de l'hormone concentratrice de la mélanine (MCH) tronqués actifs au niveau du récepteur de MCH. Les analogues de MCH tronqués sont éventuellement des dérivés de peptide modifié de MCH mammifère. Ces analogues peuvent se lier au récepteur de MCH et, de préférence, créer une transduction de signal. Les analogues de MCH possèdent une variété d'utilisations, y compris, les utilisations thérapeutiques et en tant qu'outil de recherche.

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