Heterodimers of tgf-.beta. superfamily

C - Chemistry – Metallurgy – 12 – N

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C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/495 (2006.01) C07K 14/51 (2006.01) C12N 5/10 (2006.01) C12Q 1/42 (2006.01)

Patent

CA 2124422

HETERODIMERS OF TGF-.beta. SUPERFAMILY ABSTRACT OF THE DISCLOSURE A heterodimer composed of factors belonging to a TGF-.beta. superfamily, and a composition for treatment of osteopathy containing the same, an expression vector which is autonomically replicable in an insect cell and contains one or more DNA(s) coding for a factor(s) belonging to a TGF-.beta. superfamily, and a method for preparing the heterodimer having bone-inducing activity is disclosed.

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