Quinazoline derivatives as acetylcholinesterase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/02 (2006.01) A61K 31/505 (2006.01) A61K 31/55 (2006.01) A61K 31/675 (2006.01) A61K 31/695 (2006.01) C07D 471/02 (2006.01) C07D 471/04 (2006.01) C07D 471/08 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07F 7/10 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2113115

2113115 9303034 PCTABS00019 A method of treating cognitive deficiencies is described by administering a quinazoline derivative of general formula (I) wherein A represents (IIa), (IIb), (IIc), (IId) or (IIe) in which n is 1-10, P is a bond or (CH2)m in which m is 0-10, and M is =O, =S, =NR, =CRR', (III); novel compounds of the above are also described as well as methods of manufacture and pharmaceutical compositions.

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