Prostate growth-associated membrane proteins

Details Prostate growth-associated membrane proteins Prostate growth-associated membrane proteins

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2328905

The present invention is directed to polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

L'invention concerne deux protéines de membrane associées à la croissance de la prostate (PGAMP) chez l'homme, ainsi que des polynucléotides identifiant et codant PGAMP. Elle concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Elle concerne également des procédés servant à diagnostiquer, traiter ou prévenir des maladies associées à l'expression de PGAMP.

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