Tricyclic compounds, their production and use

Details Tricyclic compounds, their production and use Tricyclic compounds, their production and use

C - Chemistry, Metallurgy

07

D

C07D 307/93 (2006.01) A61K 31/33 (2006.01) A61K 31/34 (2006.01) A61K 31/40 (2006.01) A61K 31/66 (2006.01) C07D 263/52 (2006.01) C07D 265/34 (2006.01) C07D 311/94 (2006.01) C07D 313/06 (2006.01) C07D 317/70 (2006.01) C07D 319/14 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/044 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07F 9/655 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2241666

A compound of formula (I) wherein R1 is an optionally substituted hydrocarbon, amino or heterocyclic group; R2 is H or an optionally substituted hydrocarbon group; R3 is H or an optionally substituted hydrocarbon or heterocyclic group; X is CHR4, NR4, O or S in which R4 is H or an optionally substituted hydrocarbon group; Y is C, CH or N; ring A is an optionally substituted 5- to 7-membered ring; ring B is an optionally substituted benzene ring; and m is 1 to 4, or a salt thereof, a process for producing it, an intermediate for the production and a pharmaceutical composition comprising it are provided.

L'invention concerne un composé de la formule (I) dans laquelle R<1> est un groupe hydrocarbure, amino ou hétérocyclique, éventuellement substitué; R<2> est H ou un groupe hydrocarbure, éventuellement substitué; R<3> est H ou un groupe hydrocarbure ou hétérocyclique, éventuellement subsitué; X est CHR<4>, NR<4>, O ou S, où R<4> est H ou un groupe hydrocarbure éventuellement substitué; Y est C, CH ou N; A est un cycle à 5 - 7 éléments, éventuellement substitué; B est un cycle benzénique, éventuellement substitué; et m est compris entre 1 et 4. L'invention concerne également un sel de ce composé, un procédé pour le produire, un intermédiaire utile pour cette production et une composition pharmaceutique contenant ce composé.

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