C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/551 (2006.01) A61P 25/06 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2600189
The invention relates to novel CGRP antagonists of general formula (I), in which B, R1 and R2 are defined as cited in claim 1, to their tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures and salts, in addition to the hydrates of their salts, in particular their physiologically compatible salts, with inorganic or organic acids or bases. The invention also relates to medicaments containing said compounds, to their use and to a method for their production.
La présente invention concerne de nouveaux antagonistes de CGRP représentés par la formule générale (I), dans laquelle B, R1 et R2 sont tels que définis dans la revendication 1, ainsi que leurs tautomères, isomères, diastéréoisomères, énantiomères, hydrates, mélanges et sels et les hydrates des sels, en particulier leurs sels physiologiquement acceptables comprenant des bases ou des acides inorganiques ou organiques. L'invention concerne également des médicaments contenant ces composés, ainsi que l'utilisation et des procédés de production de ces composés et de ces médicaments.
Arndt Kirsten
Doods Henri
Dreyer Alexander
Lustenberger Philipp
Mueller Stephan Georg
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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