Nitrone free radical trap treatment of dementia associated...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/44 (2006.01) A61K 31/135 (2006.01) A61K 31/167 (2006.01) A61K 31/415 (2006.01) A61K 31/4412 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2251800

Nitrone-based free radical traps are disclosed to have activity as therapeutic and prophylactic agents in the treatment of neuronal damage associated with HIV-1 virus infection, referred to in advanced stages as dementia associated with AIDS infection or AIDS Dementia Complex (ADC).

L'invention concerne des pièges à radicaux libres à base de nitrone, qui sont utiles en tant qu'agents thérapeutiques et prophylactiques dans le traitement de lésions des cellules nerveuses associées à l'infection par le virus HIV-1, connues à des stades plus avancés sous le nom de démence associée à l'infection par le virus du sida, ou complexe de démence liée au sida.

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