Tropolone derivative

Details Tropolone derivative Tropolone derivative

C - Chemistry, Metallurgy

07

C

C07C 49/747 (2006.01) A61K 31/122 (2006.01) A61K 31/136 (2006.01) A61K 31/166 (2006.01) A61K 31/17 (2006.01) A61K 31/18 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/655 (2006.01) A61P 3/02 (2006.01) A61P 3/10 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 19/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01) C07C 17/266 (2006.01) C07C 45/62 (2006.01) C07C 45/63 (2006.01) C07C 45/64 (2006.01) C07C 45/65 (2006.01) C0

Patent

CA 2432409

A tropolone derivative represented by the formula (I) which has retinoid activity and is useful as an active ingredient for medicines [R1 to R4 each represents hydrogen, alkyl, or alkoxy; ring Ar represents an aryl ring or heteroaryl ring; X represents a single bond, -N=N-, -CON(R5)-, -(C=C)nCON(R6)- , -N(R7)CON(R8)-, -SO2N(R9)-, -N(R10)- (R5 to R9 each represents hydrogen or alkyl, n is 1 to 3, and R10 represents hydrogen, alkyl, or acyl), alkylene, arylene, or heterocyclic-diyl; and Y represents hydrogen, -OR11 (R11 represents hydrogen, alkyl, or acyl), -NHR12 (R12 represents hydrogen, alkyl, acyl, or amino), or halogeno]. (I)

L'invention concerne un dérivé de tropolone représenté par la formule (I), possédant une activité de rétinoïde et utile en tant que principe actif pour des médicaments. Dans ladite formule R?1¿ à R?4 ¿représentent chacun hydrogène, alkyle ou alcoxy ; le cycle Ar représente un cycle aryle ou hétéroaryle ; X représente une liaison simple, -N=N-, -CON(R?5¿)-, -(C=C)¿n?CON(R?6¿)-, -N(R?7¿)CON(R?8¿)-, -SO?2¿N(R?9¿)-, -N(R?10¿)- (R?5¿ à R?9¿ représentant chacun hydrogène ou alkyle, n valant 1 à 3 et R?10¿ représentant hydrogène, alkyle ou acyle), alkylène, arylène ou diyle hétérocyclique ; et Y représente hydrogène, -OR?11¿ (R?11¿ représentant hydrogène, alkyle ou acyle), -NHR?12¿ (R?12¿ représentant hydrogène, alkyle, acyle ou amino), ou halogéno.

Affiliated with

Also associated with

Rating

Tropolone derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tropolone derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tropolone derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1671999