C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2439779
This invention is related to methods, systems and computer program products for determining the biological effect and/or activity of drugs, chemical substances and/or pharmaceutical compositions using their effect on DNA- methylation as a marker for their biological effect(s). The invention is further related to the use of the inventive methods, systems and computer program products in obtaining new biologically active compounds which can be used as so-called "lead" compounds for new and effective medicaments and treatment strategies of, in particular, human diseases.
La présente invention concerne des procédés, des systèmes et des produits programmes informatiques permettant de déterminer l'effet biologique et/ou l'activité de médicaments, de substances chimiques et/ou de compositions pharmaceutiques, sur la base de leur effet sur la méthylation de l'ADN, qui sert de marqueur pour leur(s) effet(s) biologique(s). La présente invention concerne également l'utilisation des procédés, des systèmes et des produits programmes informatiques selon cette invention, afin d'obtenir de nouveaux composés biologiquement actifs, qui peuvent être utilisés en tant que <= tête de série >= pour de nouveaux médicaments et de nouvelles stratégies de traitement efficaces, notamment pour des maladies humaines.
Berlin Kurt
Olek Alexander
Epigenomics Ag
G. Ronald Bell & Associates
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