Therapeutic agents for drug dependence

A - Human Necessities – 61 – K

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Details

A61K 31/495 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2349452

Disclosed is a preventive or therapeutic agent for drug dependence, comprising a 1,4-(diphenylalkyl)piperazine derivative represented by the following general formula [I] wherein R1 is lower alkoxy; R2 is lower alkoxy; "A" is lower alkylene; and "B" is lower alkylene or a salt thereof as an active ingredient. Particularly preferred is a compound represented by the following formula [II] or a salt thereof.

L'invention concerne des agents thérapeutiques ou préventifs, utiles contre la dépendance aux drogues, et contenant en tant que principe actif des dérivés de 1,4-(diphénylalkyl)pipérazine, représentés par la formule générale (I), ou des sels de ceux-ci, notamment et préférablement des dérivés représentés par la formule générale suivante (II) ou des sels de ceux-ci. Dans ces formules R<1> et R<2> représentent chacun alcoxy inférieur, et A et B représentent chacun alkylène inférieur.

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