C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01)
Patent
CA 2753782
The present invention provides an alternative scaffold for peptides displayed on filamentous phages through novel fusion proteins primarily originating from pIX. Libraries of filamentous phages can be created from fusion proteins, and a phage display system comprising a phagemid and a helper phage is a part of the invention. An aspect of the invention is a kit containing a phage display system comprising a phagemid that contains a nucleic acid encoding the fusion protein of the invention and a helper phage.
La présente invention concerne un échafaudage alternatif pour des peptides présentés à la surface de phages filamenteux par le biais de nouvelles protéines de fusion provenant principalement de pIX. Des banques de bactériophages filamenteux peuvent être créées à partir des protéines de fusion, et un système de présentation sur bactériophage comprenant un phagémide et un phage auxiliaire fait partie de l'invention. Un aspect de l'invention concerne un kit contenant un système de présentation sur phage comprenant un phagémide qui contient un acide nucléique codant pour la protéine de fusion de l'invention et un phage auxiliaire.
Borden Ladner Gervais Llp
Nextera As
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