Ligands for fpr class receptors that induce a host immune...

Details Ligands for fpr class receptors that induce a host immune... Ligands for fpr class receptors that induce a host immune...

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61P 31/18 (2006.01) C07K 7/06 (2006.01) C07K 14/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2399032

The present invention relates to the discovery of molecules that inhibit viral infection and promote a host immune response to a pathogen. More specifically, the invention disclosed herein concerns molecules that interact with a FPR class receptor, inhibit HIV infection, and stimulate an inflammatory response in a subject. Embodiments of the invention include biotechnological tools, prophylactics, therapeutics, and methods of use of the foregoing, for the study, treatment, and prevention of HIV infection and the induction of an inflammatory response in a subject.

La présente invention concerne la découverte de molécules qui inhibent l'infection virale et provoquent une réponse immunitaire de l'hôte à un agent pathogène. Plus spécifiquement, l'invention concerne des molécules qui interagissent avec un récepteur de la classe FPR, inhibent l'infection par le VIH, et provoquent une réponse inflammatoire chez un sujet. Des modes de réalisation comprennent des outils biotechnologiques, des moyens prophylactiques et thérapeutiques, et des procédés d'utilisation des éléments cités précédemment, pour l'étude, le traitement, et la prévention de l'infection par le VIH ainsi que pour produire une réponse inflammatoire chez un sujet.

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