Diagnostic image analysis with metal complexes

Details Diagnostic image analysis with metal complexes Diagnostic image analysis with metal complexes

C - Chemistry, Metallurgy

07

F

C07F 13/00 (2006.01) A61K 49/00 (2006.01) A61K 49/06 (2006.01) A61K 51/04 (2006.01) C07D 259/00 (2006.01) C07D 487/08 (2006.01) C07F 5/00 (2006.01)

Patent

CA 2188530

The present invention is directed to complexes represented by formula (I) wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, R'9, R10, R11, R12, R13, R14, M, X, Y, Z and N are defined herein for use as contrast agents in diagnostic imaging.

L'invention concerne des complexes représentés par la formule (I) dans laquelle R, R', R¿1?, R'¿1?, R¿2?, R'¿2?, R¿3?, R'¿3?, R¿4?, R'¿4?, R¿5?, R'¿5?, R¿6?, R'¿6?, R¿7?, R'¿7?, R¿8?, R'¿8?, R¿9?, R'¿9?, R¿10?, R¿11?, R¿12?, R¿13?, R¿14?, M, X, Y, Z et N sont définis dans la description et sont utiles comme agents de contraste en imagerie diagnostique.

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