Modifying drug release in suspensions of ionic resin systems

Details Modifying drug release in suspensions of ionic resin systems Modifying drug release in suspensions of ionic resin systems

A - Human Necessities

61

K

A61K 47/02 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 47/30 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2689101

The present invention includes compositions and methods for delivering one or more unit dosage units by modifying the release profile of an optionally coated drug-resin complex suspended in an ionic salt solution, wherein the optionally coated drug-resin complex includes one or more active agents loaded on to one or more ion-exchange resin particles, and wherein the release of the one or more active agents is modulated by the one or more ionic salts in solution.

La présente invention concerne des compositions et des procédés pour administrer une ou plusieurs unités de dosage unitaires en modifiant le profil de libération d'un complexe de médicament-résine facultativement revêtu en suspension dans une solution de sel ionique, où le complexe de médicament-résine facultativement revêtu comprend un ou plusieurs agents actifs chargés sur une ou plusieurs particules de résine échangeuse d'ions, et où la libération d'un ou plusieurs agents actifs est modulée par les un ou plusieurs sels ioniques en solution.

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