Gene expression profiling for identification, monitoring,...

Details Gene expression profiling for identification, monitoring,... Gene expression profiling for identification, monitoring,...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2682868

A method is provided in various embodiments for determining a profile data set for a subject with breast cancer or conditions related to breast cancer based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RNA corresponding to at least 1 constituent from Tables 1-5. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable.

L'invention porte sur divers modes de réalisation pour déterminer un ensemble de données de profil pour un sujet présentant un cancer du sein ou des conditions se rapportant à un cancer du sein sur la base d'un échantillon provenant du sujet, l'échantillon fournissant une source d'ARN. Le procédé comprend l'utilisation de l'amplification pour la mesure de la quantité d'ARN correspondant à au moins 1 constituant des Tableaux 1-5. L'ensemble de données de profil comprend la mesure de chaque constituant, et une amplification est effectuée dans des conditions de mesure qui peuvent être répétées de façon substantielle.

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